Leo Messi will return to the US when his Argentina side face Bosnia-Herzegovina at Busch Stadium.
The match is slated for November 18th with a kickoff of 7.30 local time.
The presence of the Bosnians is dependent on them qualifying for the World Cup Finals.
If they fail to qualify, they will be replaced by a team to be determined. The ex-Yugoslavian country currently lead Greece in Group G of UEFA World Cup qualifying on goal-differential with both teams are tied on 19 points.
The Bosnians host Lichtenstein on October 11th before traveling to Lithuania on October 15 to close out the final round of qualifying.
Beyond Messi, other possible stars include Argentina Sergio Aguero (Manchester City), Angel Di Maria (Real Madrid) and Gonzalo Higuain (Napoli).
Bosnia have Manchester City striker Edin Dzeko, Miralem Pjanic from Italian club Roma and former St. Louis University player Vedad Ibevsic who currently plays for Stuttgart in Germany.